Aquagenic Syringeal Acrokeratoderma

نویسندگان

  • Hsing-Chuan Lee
  • Tsen-Fang Tsai
چکیده

Aquagenic syringeal acrokeratoderma is a newly described disease entity of unclear etiology, affecting predominantly adolescents and young adults. It manifested as multiple whitish papules on the palms or rarely soles, which became accentuated after immersion in water and improved after drying the involved area. Burning, pain, pruritus or tightening sensation may be present and usually there is an association with palmar hyperhidrosis. The histopathology revealed dilated sweat duct ostia with focal mild hyperkeratosis. Most patients responded well to topical aluminum chloride, but recurrence could occur. We presented a 19-year-old healthy male with multiple whitish, translucent, asymptomatic papules mainly on his left palm for 7 years. Such a condition became more pronounced after exposure to warm water and resolved to residual smaller flesh-colored to white papules after a drying period. He reported occasional mild palmar hyperhidrosis of his left hand and had a family history of atopy. The dermatoscopy revealed dilated puncta on the papules. The histopathologic examination revealed dilatation of intracorneal eccrine ducts with mild focal hyperkeratosis and acanthosis. After receiving topical 20% anhydrous aluminum chloride nightly for 5 weeks, he reported almost disappearance of the papules when the palms were dry. (Dermatol Sinica 26: 145-150, 2008)

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Aquagenic syringeal acrokeratoderma is a newly described condition of the palms and soles characterized by hypopigmented papules and plaques, elicited after submersion in water. Symptoms include a burning pain and a tightening sensation in the palms, as well as hyperhidrosis. Initially thought to be rare, its frequent citation in the literature points to a more common entity. It is more often f...

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تاریخ انتشار 2008